I guess, you need below.. paste this code in worksheet module..
Option Explicit
Private Sub Worksheet_Change(ByVal Target As Range)
Dim KeyCells As Range
' The variable KeyCells contains the cells that will
' cause an alert when they are changed.
Set KeyCells = Range("M19")
If Not Application.Intersect(KeyCells, Range(Target.Address)) _
Is Nothing Then
' Display a message when one of the designated cells has been
' changed.
' Place your code here.
Range("L16").Value = Time
End If
End Sub
Cheers!!