Try:
Sub Demo()
Application.ScreenUpdating = False
With ActiveDocument.Range
  With .Find
    .ClearFormatting
    .Replacement.ClearFormatting
    .Text = "[0-9]{1,}"
    .Replacement.Text = ""
    .Format = True
    .Highlight = True
    .Forward = True
    .Wrap = wdFindStop
    .MatchWildcards = True
    .Execute
  End With
  Do While .Find.Found
    If .HighlightColorIndex = wdYellow Then
      .Text = "x"
      .HighlightColorIndex = wdBlack
    End If
    .Collapse wdCollapseEnd
    .Find.Execute
  Loop
End With
Application.ScreenUpdating = True
End Sub
PS:When posting code, please post formatted code and use the code tags, indicated by the # button on theposting menu. Without them, your code loses much of whatever structure it had.