I could see that this would work if one had a default option, but my form there isn't a default, so I don't think this would work.
I was thinking something like this might work, but it still fails in its current form with a Run-time error '438': Object doesn't support this property or method.
If Button1.Checked = False And Button2.Checked = False Then MsgBox "Provide reason for review", vbCritical, "Triage Hub" Exit Sub End If