You're approaching this the wrong way. Instead of using a macro enabled document as the basis of your process, you should use a macro enabled template. Word's default save format for documents is docx - which is not a macro-enabled format. Even so, provided the document remains on the same system as its template, the saved document will continue to have the functionality provided by the macro.

As for saving with a drop down list disabled, doing that depends on the type of dropdown - which you haven't told us about.